Department of Pharmacokinetics & Pharmacodynamics

Founded in 2001. Head: Alexander A. Firsov, ScD, Professor, Corresponding Member of the Russian Academy of Sciences

Faculty:

• A. A. Firsov, ScD, Professor, Corresponding Member of RAS;
• Y. A. Portnoy, Sen. Researcher;
• M. V. Golikova, PhD, Sen. Researcher;
• E. N. Strukova, PhD, Sen. Researcher;
• S. A. Dovzhenko, PhD, Sen. Researcher;
• M. B. Kobrin, Sen. Researcher;
• N. E. Grammatikova, PhD, Sen. Researcher;
• I. Y. Lubenko, Engineer;
• I. V. Belitskii, Engineer;
• E. E. Kuleshova, Sen. Technician;
• K. N. Alieva, PhD student

Main Research Areas:

• PK/PD studies using in vitro simulations of human antibiotic pharmacokinetics
• Predicting resistant mutant enrichment when simulating clinically relevant antibiotic dosing regimens
• Pre-clinical and clinical pharmacokinetics of antibiotics and other agents

Major Achievements:

• Development of methodology of PK/PD studies using in vitro simulations of antibiotic pharmacokinetics
• Development of a general approach to predict the effective concentrations and dosing regimens with novel antibiotics
• Modeling of bacterial resistance development using in vitro dynamic models
• Predicting “anti-mutant” antibiotic dosing

List of selected references is HERE

• Research collaboration:
• Research Institute of Antimicrobial Chemotherapy (Smolensk)
• Research Institute of Infections in Childhood (Saint-Petersburg)
• Harvard University (Cambridge, USA)
• The University of New Jersey (Newark, USA)

Contacts: Phones: +7(495)708-3341, +7(499)245-2095; E-mail: kindyn@gmail.com