Department of Pharmacokinetics & Pharmacodynamics

Founded in 2001 by Alexander A. Firsov, ScD, Professor, Corresponding Member of the Russian Academy of Sciences









  • · M. V. Golikova, PhD, Head of Department;

  •  E. N. Strukova, PhD, Sen. Researcher;

  • S. A. Dovzhenko, PhD, Sen. Researcher

  •  M. B. Kobrin, Sen. Researcher;

  • N. E. Grammatikova, PhD, Sen. Researcher

  • Y. A. Portnoy, Sen. Researcher

  • K. N. Alieva, Junior Researcher;

  • A.V. Filimonova, Junior Researcher;

  • I. V. Belitskii, Engineer;

  • E. E. Kuleshova, Engineer;

  • D.I. Yamalieva, Sen. Technician;

  • A.A. Kusnezova, Sen. Technician

Main Research Areas:

  • PK/PD studies using in vitro simulations of human antibiotic pharmacokinetics
  • Predicting resistant mutant enrichment when simulating clinically relevant antibiotic dosing regimens
  • Pre-clinical and clinical pharmacokinetics of antibiotics and other agents

Major Achievements:

  • Development of methodology of PK/PD studies using in vitro simulations of antibiotic pharmacokinetics
  • Development of a general approach to predict the effective concentrations and dosing regimens with novel antibiotics
  • Modeling of bacterial resistance development using in vitro dynamic models
  • Predicting “anti-mutant” antibiotic dosing


Research collaboration:

  • Research Institute of Antimicrobial Chemotherapy (Smolensk)

  • Mount-Obern Hospital (Cambridge, USA)

Contacts: Phones: +7(495)708-3341, +7(499)245-2095; E-mail: