Department of Pharmacokinetics & Pharmacodynamics

Founded in 2001 by Alexander A. Firsov, ScD, Professor, Corresponding Member of the Russian Academy of Sciences

Faculty:

• · M. V. Golikova, PhD, Head of Department;

•  E. N. Strukova, PhD, Sen. Researcher;

• S. A. Dovzhenko, PhD, Sen. Researcher

•  M. B. Kobrin, Sen. Researcher;

• N. E. Grammatikova, PhD, Sen. Researcher

• Y. A. Portnoy, Sen. Researcher

• K. N. Alieva, Junior Researcher;

• A.V. Filimonova, Junior Researcher;

• I. V. Belitskii, Engineer;

• E. E. Kuleshova, Engineer;

• D.I. Yamalieva, Sen. Technician;

• A.A. Kusnezova, Sen. Technician

Main Research Areas:

• PK/PD studies using in vitro simulations of human antibiotic pharmacokinetics
• Predicting resistant mutant enrichment when simulating clinically relevant antibiotic dosing regimens
• Pre-clinical and clinical pharmacokinetics of antibiotics and other agents

Major Achievements:

• Development of methodology of PK/PD studies using in vitro simulations of antibiotic pharmacokinetics
• Development of a general approach to predict the effective concentrations and dosing regimens with novel antibiotics
• Modeling of bacterial resistance development using in vitro dynamic models
• Predicting “anti-mutant” antibiotic dosing

Research collaboration:

• Research Institute of Antimicrobial Chemotherapy (Smolensk)

• Mount-Obern Hospital (Cambridge, USA)

Contacts: Phones: +7(495)708-3341, +7(499)245-2095; E-mail: kindyn@gmail.com