Department of Pharmacokinetics & Pharmacodynamics
Founded in 2001. Head: Alexander A. Firsov, ScD, Professor, Corresponding Member of the Russian Academy of Sciences
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Faculty: A. A. Firsov, ScD, Professor, Corresponding Member of RAS;
Y. A. Portnoy, Sen. Researcher;
M. V. Golikova, PhD, Sen. Researcher;
E. N. Strukova, PhD, Sen. Researcher;
S. A. Dovzhenko, PhD, Sen. Researcher;
M. B. Kobrin, Sen. Researcher;
N. E. Grammatikova, PhD, Sen. Researcher;
I. Y. Lubenko, Engineer;
I. V. Belitskii, Engineer;
E. E. Kuleshova, Sen. Technician;
K. N. Alieva, PhD student
Main Research Areas:
- PK/PD studies using in vitro simulations of human antibiotic pharmacokinetics
- Predicting resistant mutant enrichment when simulating clinically relevant antibiotic dosing regimens
- Pre-clinical and clinical pharmacokinetics of antibiotics and other agents
Major Achievements:
- Development of methodology of PK/PD studies using in vitro simulations of antibiotic pharmacokinetics
- Development of a general approach to predict the effective concentrations and dosing regimens with novel antibiotics
- Modeling of bacterial resistance development using in vitro dynamic models
- Predicting “anti-mutant” antibiotic dosing
List of selected references is HERE
Research collaboration:
- Research Institute of Antimicrobial Chemotherapy (Smolensk)
- Research Institute of Infections in Childhood (Saint-Petersburg)
- Harvard University (Cambridge, USA)
- The University of New Jersey (Newark, USA)
Contacts: Phones: +7(495)708-3341, +7(499)245-2095; E-mail: kindyn@gmail.com