Department of Pharmacokinetics & Pharmacodynamics

Founded in 2001. Head: Alexander A. Firsov, ScD, Professor, Corresponding Member of the Russian Academy of Sciences

Faculty: A. A. Firsov, ScD, Professor, Corresponding Member of RAS;

Y. A. Portnoy, Sen. Researcher;

M. V. Golikova, PhD, Sen. Researcher;

E. N. Strukova, PhD, Sen. Researcher;

S. A. Dovzhenko, PhD, Sen. Researcher;

M. B. Kobrin, Sen. Researcher;

N. E. Grammatikova, PhD, Sen. Researcher;

I. Y. Lubenko, Engineer;

I. V. Belitskii, Engineer;

E. E. Kuleshova, Sen. Technician;

K. N. Alieva, PhD student

Main Research Areas:

  • PK/PD studies using in vitro simulations of human antibiotic pharmacokinetics
  • Predicting resistant mutant enrichment when simulating clinically relevant antibiotic dosing regimens
  • Pre-clinical and clinical pharmacokinetics of antibiotics and other agents

    Major Achievements:

    • Development of methodology of PK/PD studies using in vitro simulations of antibiotic pharmacokinetics
    • Development of a general approach to predict the effective concentrations and dosing regimens with novel antibiotics
    • Modeling of bacterial resistance development using in vitro dynamic models
    • Predicting “anti-mutant” antibiotic dosing

      List of selected references is HERE

      Research collaboration:

    • Research Institute of Antimicrobial Chemotherapy (Smolensk)
    • Research Institute of Infections in Childhood (Saint-Petersburg)
    • Harvard University (Cambridge, USA)
    • The University of New Jersey (Newark, USA)

      Contacts: Phones: +7(495)708-3341, +7(499)245-2095; E-mail:

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